The 95-year-old monarch, who is experiencing mild symptoms of a cold, is self-isolating at Windsor Castle.
Concerns about the longest reigning sovereign nation have intensified given its age and recent health concerns.
But Buckingham Palace said the monarch will be sitting at his desk doing light duties in the coming days.
Almost every Wednesday, the Queen holds audiences with Boris Johnson in person or by phone, and more recently has one or two diplomatic audiences a week with ambassadors via video link.
She is following advice to self-isolate after testing positive on Sunday, but her diagnosis comes as Mr Johnson prepares on Monday to end the legal obligation to self-isolate from next week.
The Queen will also work from her red boxes, which are sent to her every day and contain policy papers, Foreign Office telegrams, letters and other government documents from government ministers and Commonwealth representatives to be read and, if necessary, approved and signed.
She is accompanied by her dogs – her elderly dorgi Candy, corgi puppy Muik and another young corgi.
Monarch, if she’s feeling well enough, will also likely look into Racing Post.
She took the win on Sunday when her horse Kincardine won the Blood Herd Agents Federation Maiden Hurdle in Newbury.
Her diagnosis follows a string of cases among the royal family, with the Prince of Wales seeing his mother the week he tested positive, and the Duchess of Cornwall also self-isolating after contracting the virus.
The Queen has just reached her historic platinum 70th birthday on the throne, February 6th.
The Royal Court has its own physicians and the Queen’s physicians will be on hand to care for and oversee the Head of State, and Professor Sir Hugh Thomas, Head of the Medical Court and the Queen’s Physician, is expected to be in charge.
The Queen has a number of important events planned for next month.
On March 2, she will host a diplomatic reception where she will meet with hundreds of members of the diplomatic corps in Windsor.
She is also due to attend a Commonwealth service at Westminster Abbey on March 14, followed by a memorial service for the Duke of Edinburgh, also at the Abbey, on March 29.
Just a few weeks ago, she took up her usual duties, hosting her biggest reception in months at Sandringham on the eve of her platinum jubilee, and a few days later she held her first private audience with the Prime Minister. after many weeks.
She now regularly uses a cane and recently opened up about her mobility problems, telling two senior officers during a reception at Windsor Castle, “Well, as you can see, I can’t move” when asked how she felt.
The Queen, whose husband Philip died 10 months ago, has spent most of the pandemic in the safety of Windsor Castle.